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Alzheimer's Disease
The Department of the Planet Earth provides a good deal of information about Alzheimer's Disease and dementia. The paper on Alzheimer's Disease Prevention is a comprehensive look at this serious and dangerous affliction. Following the link table below is an extract of this publication and links to a printable PDF download.
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Alzheimer Disease Is Substantially Preventable in the United States. - Review of Risk Factors, Therapy Options, and the Prospects for an Expert System.
by Erik T. Jansson
Department of the Planet Earth, Inc.
701 E Street, SE, Suite 200
Washington, DC 20003, USA
Tel.: +1 202 543 5450; Fax: +1 202 543 4791
Correspondence E-mail: planetearth@erols.com
August 2004
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Table of Contents
Abstract:
Epidemiology studies, including both regional incidence and the analysis of specific risk factors for Alzheimer's disease indicate that substantial prevention of the disease, in the 50 to 70 percent range, is a practical possibility for the United States. Epidemiology has identified a rich diversity of specific prevention strategies relating to nutrition, dietary supplements, lifestyle, food and environmental toxins, and in some cases medication, many of which have a capacity to reduce Alzheimer's risk by 50 percent or more. The interaction of these risk factors with brain biology is increasingly understood. In contrast, therapeutic strategies for un-prevented Alzheimer's generally prove incapable of delaying disease progression by more than 3 to 12 months, because extensive brain cell death occurs even in preclinical or mild cases. A public health program aimed at prevention can be fashioned with expert software packages, based on already identified risk factors. Such statistical analysis should allow the prediction of individual and group Alzheimer's risks of sufficient power to instruct the formulation of lifestyle, nutritional and environmental programs to substantially reduce disease incidence. A less satisfactory but complementary alternative is very early disease detection with therapeutic strategies focused on retardation of brain cell death, so that the person dies of another cause before the disease is clinically manifested.
Key Words: Alzheimer's, risk, prevention, therapy, incidence, aluminum, fatty acid, metal, antioxidant, nutrition, expert system
Table of Contents
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Executive Summary
Table 1. Best Prevention Options With Potential to Alter
Alzheimer's Risk By 50 Percent or More.
Table 2. Best Available Therapeutic Options for Alzheimer's.
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Comparison of Prevention and Therapy Prospects Recommends Very Early Identification of AD, or Software Prediction Systems.
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Comparison of Prevention Options That May Reduce AD Risk by Fifty Percent or More, and Related Therapy Options.
3.1. Aluminum
Table 3. Substances in Biology, Food or Drugs That
Chelate or Interact With Aluminum.
3.2. Animal Fat, Fish Oil, Vegetable Fatty Acids
3.3. Anti-Oxidant Food and Nutritional Supplements
3.4. Wine and Alcohol
3.5. Folic Acid, Vitamin B Status, and Homocysteine
3.6. Soybeans and Beans
3.7. Alpha-Lipoic Acid
3.8. Flavonoids Other than Wine (Including Curcumin,
Blueberries and Ginkgo Biloba
3.9. Melatonin, Bright Light Therapy, and DHEA
3.10. Vaccination, Infection and Cyanotoxins
3.11. Interaction With Vascular Factors
3.12. Stimulation of the Mind: Exercise, Social Relationships, Leisure |
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Zinc and Copper in AD.
4.1. - 4.3. Zinc
4.4. Copper
4.5. Estimation of Effect of Normal Serum Zinc Restoration on AD Risk
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Conclusion: Prospects for AD Prevention on a Population Scale and For Expert System Development
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References
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RESOURCES
A review: Aluminum as a causative co-factor for the “dementia” of Alzheimer’s disease.
PDF (114 KB)